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Alivio Care Clinic
Pediatric Neurorehabilitation Centre
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Child Neurology: Parainfectious Anti-NMDAREncephalitis With Anti-MOG and Anti-AQP4Seropositivity in an Infant
Abstract Overlap syndromes of anti-N-methyl-D-aspartate (NMDA) receptor encephalitis and myelin oligodendrocyte glycoprotein (MOG) or aquaporin-4 (AQP4)–mediated demyelination, ei- ther concurrently or sequentially, have been increasingly recognized. We report a 7-month-old infant who presented with 7 days of fever, seizures, irritability, and signs of meningeal irritation. Initial workup suggested acute meningoencephalitis; therefore, the child was treated with antibiotics,
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